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Mouse ALK-1 quantitates mouse ALK-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse ALK-1.
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2. Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : Acvrlk1, Alk1
基因ID : (Mouse) 11482
基因符号 : Acvrl1
蛋白别名 : activin receptor-like kinase 1, Acvrl1, serine/threonine-protein kinase receptor R3, SKR3, TGF-B superfamily receptor type I, TSR-I, unnamed protein product
UniProt ID (Mouse) Q61288