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Mouse Activin A quantitates mouse Activin A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Activin A.
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : Inhba
基因ID : (Mouse) 16323
基因符号 : Inhba
蛋白别名 : Activin beta-A chain, Inhibin beta A chain
UniProt ID (Mouse) Q04998