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The Mouse Calcitonin Gene Related Peptide 1 (CGRP1) ELISA quantitates CGRP1 in serum, plasma, and other biological fluids
The Mouse Calcitonin Gene Related Peptide 1 (CGRP1) solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the binding of the second (detector) antibody to the target on a different epitope from the capture antibody. An antibody conjugated with enzyme binds the formed sandwich. After incubation and washing steps to rid the microplate of unbound substances, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation:
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CA, Calc, Calc1, Calca, Cgrp, CGRP-1, CGRP1, Ct, Ctn
基因ID : (Mouse) 12310
基因符号 : Calca
蛋白别名 : Alpha-type CGRP, Calcitonin, Calcitonin gene-related peptide 1, Calcitonin gene-related peptide I, CGRP-I, CGRP1, MGC126648, RAT calcitonin
UniProt ID (Mouse) P70160