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Mouse Gremlin-1 quantitates mouse Gremlin-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Gremlin-1.
In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : Cktsf1b1, Drm, Grem, ld
基因ID : (Mouse) 23892
基因符号 : Grem1
蛋白别名 : BMP antagonist, cysteine knot superfamily 1, BMP antagonist 1, down-regulated in Mos-transformed cells protein, down-regulated in v-mos-transformed cells, unnamed protein product
UniProt ID (Mouse) O70326