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Invitrogen
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Mouse IL-17BR quantitates mouse IL-17BR in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IL-17BR.
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : Evi27, IL-17ER, IL-17Rh1, Il17br, Il17rb, IL17RH1
基因ID : (Mouse) 50905
基因符号 : Il17rb
蛋白别名 : ecotropic viral integration site 27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17B, IL-20, MGC138900, MGC138901, MGC5245, ZCYTO7, IL-17ER, IL-17RB, interleukin 17B receptor, Interleukin-17 receptor B, Interleukin-17B receptor
UniProt ID (Mouse) Q9JIP3