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Invitrogen
Mouse IL-18 BPc ELISA Kit
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产品规格
检测灵敏度
22 pg/mL
测定范围
22-5,000 pg/mL
检测样本类型/体积
{Serum=50 µL, Plasma=50 µL, Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
IL18BPc
均相（无需洗涤）
Mouse
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Mouse IL-18 BPc quantitates mouse IL-18 BPc in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IL-18 BPc.
靶标信息
The IL18BPc gene encodes one of the isoforms of the interleukin-18 binding protein (IL-18BP), a crucial component in immune system regulation. Located in humans, IL18BPc is among four isoforms, alongside hIL-18BPa, b, and d, with hIL-18BPa being the predominant form. Both hIL-18BPa and hIL-18BPc effectively neutralize interleukin-18 (IL-18), a pro-inflammatory cytokine produced by T cells and NK cells, thereby mitigating its activity. This interaction is essential as IL-18 is implicated in several inflammatory and cardiovascular diseases. IL-18BP acts as a natural inhibitor, demonstrating a high affinity for IL-18, which makes it a significant focus for therapies targeting cytokine pathways in immunotherapy. Its ability to antagonize IL-18 highlights its potential as an immune checkpoint in cancer therapy, offering alternatives to enhance treatment efficacy and tolerability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名 : IL18 BPC, IL18BP, IL-18BP, IL-18BPC, Interleukin 18 binding protein
