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Mouse IL-36 beta/IL-1F8 quantitates mouse IL-36 beta/IL-1F8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IL-36 beta/IL-1F8.
IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP. Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown. The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : 2310043N20Rik, Fil1e, Il1f8, Il36b
基因ID : (Mouse) 69677
基因符号 : Il1f8
蛋白别名 : IL-1F8, Interleukin, Interleukin-1 family member 8, Interleukin-36 beta
UniProt ID (Mouse) Q9D6Z6