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The Mouse IL-6 Receptor Rapid ELISA Kit quantitates IL-6 Receptor (CD126) in serum and plasma
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CD126, IL-6R, Il6r, Il6ra
基因ID : (Mouse) 16194
基因符号 : Il6ra
蛋白别名 : CD126, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6 Receptor, il-6 receptor alpha, ILN, Interleukin, MGC104991, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, Interleukin-6 receptor subunit alpha
UniProt ID (Mouse) P22272