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The Mouse MDC (CCL22) ELISA quantitates Ms MDC in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms MDC.
原理方法
The Mouse MDC solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ABCD-1, Abcd1, Ccl22, DCBCK, MDC, Scya22
基因ID : (Mouse) 20299
基因符号 : Ccl22
蛋白别名 : Activated B and dendritic cell-derived, CC chemokine ABCD-1, Small-inducible cytokine A22, AW060611, MGC108943, MGC34554, RP24-69A20.1, C-C motif chemokine 22, dendritic cell and B cell derived chemokine, SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED), small inducible cytokine subfamily A, member 22, small inducible cytokine subfamily A22
UniProt ID (Mouse) O88430