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Rat MIP-1alpha quantitates rat MIP-1alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat MIP-1alpha.
Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : G0S19-1, LD78alpha, MIP-1a, MIP-1alpha, MIP1-(a), MIP1-alpha, Mip1a, Scya3
基因ID : (Mouse) 20302, (Rat) 25542
基因符号 : Ccl3, Ccl3
蛋白别名 : Ccl3, chemokine (C-C motif) ligand 3, heparin-binding chemotaxis protein, L2G25B, L2G25B protein precursor, Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3), macrophage inflammatory protein 1-alpha, macrophage inflammatory protein-1alpha, MIP-1-alpha, MIP1 (a), mip1 alpha, RP23-320E6.7, H-MIP-1-alpha, LD78-alpha, Mip1a, SIS-alpha, small-inducible cytokine A3, TY-5, unnamed protein product
UniProt ID (Mouse) P10855, (Rat) P50229