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The Mouse TARC/CCL17 ELISA quantitates Ms TARC in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms TARC.
原理方法
The Mouse TARC solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking and activation of mature T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : Abcd-2, Ccl17, Scya17, Scya17l, Tarc
基因ID : (Mouse) 20295
基因符号 : Ccl17
蛋白别名 : ABCD-2, C-C motif chemokine, C-C motif chemokine 17, CC chemokine TARC, small inducible cytokine subfamily A17, Small-inducible cytokine A17, Thymus and activation-regulated chemokine
UniProt ID (Mouse) Q9WUZ6