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Invitrogen
Multispecies MAPK Family Activation InstantOne™ ELISA Kit
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产品规格
检测样本类型/体积
{Cell lysate=20 µL}
手工操作时间
1 hr 20 min
总时间
1 hr 10 min
均相（无需洗涤）
No
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Capture Antibody
Detection Antibody Reagent
InstantOne™ Assay Plate
Cell Lysis Buffer
Enhancer Solution
Wash Buffer (10X)
Substrate Reagent (TMB)
Stop Solution
Positive Control Cell Lysate (lyophilized)
Plate seal
Detection Antibody Reagent
InstantOne™ Assay Plate
Cell Lysis Buffer
Enhancer Solution
Wash Buffer (10X)
Substrate Reagent (TMB)
Stop Solution
Positive Control Cell Lysate (lyophilized)
Plate seal
运输条件
Wet ice
储存
2-8°C
蛋白名称
JNK1/JNK2/JNK3/ERK1/2/p38 MAPK alpha
均相（无需洗涤）
Human
检测试剂盒格式
InstantOne ELISA
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
The InstantOne™ ELISA is specifically engineered for accurate measurement of phosphorylated ERK 1/2 (human, mouse, hamster), p38 MAPK (human, mouse), and JNK 1/2 (human, mouse) in cell lysates. Detection of these phosphorylated molecules in rat is also expected. The InstantOne™ ELISA kit allows for fast analysis of samples in approximately one hour. All reagents used in a traditional sandwich ELISA are added in solution to a plate followed by a wash step and detection with the TMB colorimetric substrate.
靶标信息
MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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生物信息学
基因别名 : CSBP, CSBP1, CSBP2, CSPB1, ERK, ERK-1, ERK-2, ERK1, ERK2, ERT1, ERT2, EXIP, HS44KDAP, HUMKER1A, MAPK2, Mxi2, NS13, p38, p38ALPHA, p40, p41, p41mapk, p42-MAPK, P42MAPK, p44-ERK1, p44-MAPK, P44ERK1, P44MAPK, PRKM1, PRKM14, PRKM15, PRKM2, PRKM3, RK, SAPK2A
基因ID : (Human) 5594, (Human) 1432, (Human) 5595
基因符号 : MAPK1, MAPK14, MAPK3
蛋白别名 : CSAID-binding protein, cytokine suppressive anti-inflammatory drug binding protein, encoded by transcript variant 4, p38 MAP kinase, encoded by transcript variant 5, Erk1, cancer susceptibility protein, ERK1b, ERK1c, Erk2, extracellular signal-regulated kinase 1, extracellular signal-regulated kinase 2, extracellular signal-related kinase 1, insulin-stimulated MAP2 kinase, MAP kinase 1, MAP kinase 14, MAP kinase 2, MAP kinase Mxi2, MAP kinase p38 alpha, MAPK, MAPK 1, MAPK 2, MAPK14, MAX-interacting protein 2, microtubule-associated protein 2 kinase, mitogen-activated protein kinase 2, mitogen-activated protein kinase p38 alpha, p38 mitogen activated protein kinase, p38alpha Exip, protein tyrosine kinase ERK2, SAPK2a, CSAIDS binding protein 1, stress-activated protein kinase 2A, unnamed protein product
UniProt ID (Human) P28482, (Human) Q16539, (Human) P27361
