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Rat CD138 (Syndecan-1) ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of rat Syndecan-1 in serum, plasma, and cell culture supernatants.
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : HSPG, Sdc1, Synd1, SYNDECA, Syndecan
基因ID : (Rat) 25216
基因符号 : Sdc1
蛋白别名 : CD antigen 138, sCD138, soluble CD138, Syndecan1, CD138, SYND1, Syndecan-1
UniProt ID (Rat) P26260