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Rat Decorin quantitates rat Decorin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat Decorin.
Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因ID : (Rat) 29139
基因符号 : Dcn
蛋白别名 : bone proteoglycan II, dermatan sulfate proteoglycan-II (decorin), Dermatan sulphate proteoglycans II (DSPG2), Small leucine rich protein 1B, DSPG, PG-S2, PG40
UniProt ID (Rat) Q01129