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Rat JAM-A quantitates rat JAM-A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat JAM-A.
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : F11r, Jam1
基因ID : (Rat) 116479
基因符号 : F11r
蛋白别名 : CD321, F11 R, JAM-1, JAM-A, Junctional adhesion molecule 1, Junctional adhesion molecule A
UniProt ID (Rat) Q9JHY1