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Invitrogen
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Monkey IGF-2 quantitates monkey IGF-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey IGF-2.
The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名 : FLJ22066, FLJ44734, H-IGF-2, IGF, Insulin like growth factor