TSKU ELISA Kits

靶标信息

The TSKU gene encodes Tsukushi, a member of the small leucine-rich proteoglycan (SLRP) family, playing crucial roles in cellular signaling, growth, and development. Tsukushi is characterized by its involvement in various biological processes, including immune regulation, tissue remodeling, and metabolic homeostasis. It is a hepatokine released in response to conditions like nonalcoholic fatty liver disease (NAFLD), influencing metabolic traits and contributing to conditions such as dyslipidemia and cardiovascular diseases. Tsukushi impacts energy expenditure by modulating brown fat thermogenesis, thereby affecting metabolic homeostasis and obesity-related metabolic traits. As an extracellular matrix component, Tsukushi participates in signaling pathways that regulate cell proliferation, migration, and differentiation, impacting organ development and pathophysiological processes. Its role in metabolic and inflammatory diseases presents it as a potential biomarker and therapeutic target in conditions characterized by altered metabolic and inflammatory states. Ongoing research further elucidates Tsukushi's mechanisms and interactions, contributing to our understanding of its multifunctional roles in health and disease.

同义词

9530051K01Rik; E2ig4; E2-induced gene 4 protein; Early insulin-induced hepatic gene protein; Eiih; hepatic protein EIIH; leucine rich repeat containing 54; leucine-rich repeat-containing protein 54; LRRC54; Tsk; Tsku; Tsukushi; tsukushi homolog; tsukushi small leucine rich proteoglycan homolog; tsukushi, small leucine rich proteoglycan; tsukushin; UNQ850/PRO1788