MERTK ELISA Kits

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human MERTK can be quantified in various samples, including plasma, serum, cell lysate, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human MERTK can be quantified in various samples, including plasma, serum, cell lysate, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human MERTK can be quantified in various samples, including plasma, serum, cell lysate, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human MERTK can be quantified in various samples, including plasma, serum, cell lysate, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits are ready-to-use and quality tested for sensitivity, specificity, precision and lot-to-lot consistency.

靶标信息

MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

同义词

c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer

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"mertk"总计查到2个结果

2个结果

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样品容量

价格

对比

Invitrogen

Human Mer (MERTK) ELISA Kit

Invitrogen

Human Mer (MERTK) ELISA Kit

2 篇参考文献

灵敏度 6.96 pg/mL

测定范围 11.72-750 pg/mL

样品容量

Serum

5 µL

Plasma

5 µL

Cell Lysate

5 µL

总时间

3 hr 30 min

(1 hr 20 min hands-on)

价格

货号 BMS2285

Invitrogen

Human Mer (MERTK) ELISA Kit

Invitrogen

Human Mer (MERTK) ELISA Kit

1 篇参考文献

灵敏度 0.15 ng/mL

测定范围 0.15-40 ng/mL

样品容量

Plasma

50 µL

Serum

50 µL

Supernatant

100 µL

总时间

4 hr 45 min

(1 hr 20 min hands-on)

价格

货号 EHMER

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