靶标信息
Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.
同义词
AL023044; AW123854; RGD1564996; TAJ; TAJ-alpha; TNF receptor superfamily member 19; Tnfrsf19; Toxicity and JNK inducer; TRADE; TROY; tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19; UNQ1888/PRO4333