Reduction in intracellular calcium levels inhibits myoblast differentiation.
Authors Porter George A Jr; Makuck Ryan F; Rivkees Scott A;
JournalJ Biol Chem
PubMed ID12042317
'In myocytes, calcium plays an important role in intracellular signaling and contraction. However, the ability of calcium to modulate the differentiation of striated muscle cells is poorly understood. To examine this issue we studied C2C12 cells, which is a myoblast cell line that differentiates in vitro. First, we observed that ... More