The Golgi apparatus of rat pachytene spermatocytes during spermatogenesis.
AuthorsSuarez-Quian CA, An Q, Jelesoff N, Dym M
JournalAnat Rec
PubMed ID1996781
'A morphological and immunocytochemical study of the Golgi apparatus in pachytene spermatocytes was performed in an effort to correlate the structure and function of this organelle during meiotic prophase. In stages I-III of the cycle, the Golgi complex of pachytene spermatocytes is a flattened discoid, 0.5-1 microns in diameter, composed ... More
Glutathione-S-transferase induces murine dermatitis that resembles human atopic dermatitis.
The molecular and functional basis of allergen-induced inflammation seen in atopic dermatitis (AD) remains undefined.
Lymphangiogenesis does not occur in breast cancer.
AuthorsAgarwal B, Saxena R, Morimiya A, Mehrotra S, Badve S,
JournalAm J Surg Pathol
PubMed ID16224211
Breast cancer metastasis predominantly occurs via lymphatic vessels. However, the study of lymphatic vessels and lymphangiogenesis has been hampered by lack of specific markers. Recently, antibodies directed against M2A (D2-40), Podoplanin, and Prox-1 that specifically mark lymphatic vessels in paraffin-embedded sections have become available. These were used to study lymphangiogenesis ... More
Immunocytochemical localization of the epidermal growth factor receptor in mouse testis.
AuthorsSuárez-Quian CA, Niklinski W
JournalBiol Reprod
PubMed ID2291927
The distribution of the epidermal growth factor receptor (EGFR) in mouse testis was ascertained by immunocytochemical methodology using a polyclonal antibody (RK2) shown previously to recognize the cytoplasmic domain of the human (A431 cells), murine (Swiss 3T3 cells), and chicken (CK 109 cells) EGFR. Initial studies performed to determine the ... More
Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse.
AuthorsIwaki T, Sandoval-Cooper MJ, Paiva M, Kobayashi T, Ploplis VA, Castellino FJ
JournalAm J Pathol
PubMed ID11891199
In humans, maternal fibrinogen (Fg) is required to support pregnancies by maintaining hemostatic balance and stabilizing uteroplacental attachment at the fibrinoid layer found at the fetal-maternal junction. To examine relationships between low Fg levels and early fetal loss, a genetic model of afibrinogenemia was developed. Pregnant mice homozygous for a ... More