Vitronectin gene expression in vivo. Evidence for extrahepatic synthesis and acute phase regulation.
AuthorsSeiffert D, Crain K, Wagner NV, Loskutoff DJ
JournalJ Biol Chem
PubMed ID7519600
'A competitive polymerase chain reaction (PCR) assay was developed to quantitate vitronectin (Vn) mRNA in murine tissues using a synthetic RNA as an external standard. Although the liver contained the highest concentration of Vn mRNA, significant levels were also detected in the brain (25-fold less) and in adipose tissue, heart, ... More