Lymphangiogenesis does not occur in breast cancer.
AuthorsAgarwal B, Saxena R, Morimiya A, Mehrotra S, Badve S,
JournalAm J Surg Pathol
PubMed ID16224211
Breast cancer metastasis predominantly occurs via lymphatic vessels. However, the study of lymphatic vessels and lymphangiogenesis has been hampered by lack of specific markers. Recently, antibodies directed against M2A (D2-40), Podoplanin, and Prox-1 that specifically mark lymphatic vessels in paraffin-embedded sections have become available. These were used to study lymphangiogenesis ... More