Pleomorphic hyalinizing angiectatic tumor of soft parts: immunohistochemical study including the expression of vascular endothelial growth factor.
AuthorsGroisman GM, Bejar J, Amar M, Ben-Izhak O,
JournalArch Pathol Lab Med
PubMed ID10705399
'We report morphologic, flow cytometric, and immunohistochemical findings in two cases of pleomorphic hyalinizing angiectatic tumor of soft parts. Both patients were middle-aged women with subcutaneous lesions located in the lower extremity. The tumors consisted of sheets of spindled and pleomorphic cells with frequent intranuclear pseudoinclusions associated with clusters of ... More
Combined pleomorphic xanthoastrocytoma-ganglioglioma of the cerebellum.
AuthorsEvans AJ, Fayaz I, Cusimano MD, Laperriere N, Bilbao JM,
JournalArch Pathol Lab Med
PubMed ID11079032
'Combined pleomorphic xanthoastrocytoma-ganglioma is a rare neoplasm, occurring in patients younger than 30 years. The clinical course of these tumors is difficult to predict because of their rarity. We report a case of combined pleomorphic xanthoastrocytoma-ganglioma that, in addition to the patient''s age, is unusual in several respects. The lesion ... More
Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.
AuthorsGerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H
JournalJ Immunol
PubMed ID6206131
The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present investigation was to clarify whether the Ki-67 nuclear antigen is restricted in its expression to certain phases of the cell cycle. All experiments consistently showed that the Ki-67 nuclear antigen ... More