Scrotal leiomyomas with atypical bizarre nuclei are rare, which might be misdiagnosed as malignant tumor. We describe a case of scrotal bizarre leiomyoma in a 65-yr-old man. The tumor was a 1 cm-sized, well circumscribed, oval mass arising from the tunica dartos muscle. Histologically, it was formed by whorling bundles ... More
Cultivation-dependent plasticity of melanoma phenotype.
AuthorsKodet O, Dvoránková B, Krejcí E, Szabo P, Dvorák P, Štork J, Krajsová I, Dundr P, Smetana K, Lacina L,
Journal
PubMed ID23757003
Malignant melanoma is a highly aggressive tumor with increasing incidence and high mortality. The importance of immunohistochemistry in diagnosis of the primary tumor and in early identification of metastases in lymphatic nodes is enormous; however melanoma phenotype is frequently variable and thus several markers must be employed simultaneously. The purposes ... More