Interaction and regulation of subcellular localization of CED-4 by CED-9.
AuthorsWu D, Wallen HD, Nuñez G
JournalScience
PubMed ID9027313
The Caenorhabditis elegans survival gene ced-9 regulates ced-4 activity and inhibits cell death, but the mechanism by which this occurs is unknown. Through a genetic screen for CED-4-binding proteins, CED-9 was identified as an interacting partner of CED-4. CED-9, but not loss-of-function mutants, associated specifically with CED-4 in yeast or ... More