Calreticulin Represses E-cadherin Gene Expression in Madin-Darby Canine Kidney Cells via Slug.
AuthorsHayashida Y, Urata Y, Muroi E, Kono T, Miyata Y, Nomata K, Kanetake H, Kondo T, Ihara Y,
JournalJ Biol Chem
PubMed ID16943193
Calreticulin (CRT) is a multifunctional Ca(2+)-binding molecular chaperone in the endoplasmic reticulum. In mammals, the expression level of CRT differs markedly in a variety of organs and tissues, suggesting that CRT plays a specific role in each cell type. In the present study, we focused on CRT functions in the ... More