Myocardin expression is regulated by nkx2.5, and its function is required for cardiomyogenesis.
AuthorsUeyama T, Kasahara H, Ishiwata T, Nie Q, Izumo S,
JournalMol Cell Biol
PubMed ID14645532
Nkx2.5 (also known as Csx) is an evolutionarily conserved cardiac transcription factor of the homeobox gene family. Nkx2.5 is required for early heart development, since Nkx2.5-null mice die before completion of cardiac looping. To identify genes regulated by Nkx2.5 in the developing heart, we performed subtractive hybridization by using RNA ... More