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Invitrogen
CD186 (CXCR6) Monoclonal Antibody (DANID2), PE, eBioscience™
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CD186 (CXCR6) Antibody (12-9186-82) in Flow
C57BL/6 mouse splenocytes were stained with CD3 Monoclonal Antibody, FITC (Product # 11-0031-82), CD69 Monoclonal Antibody, Super Bright 436 (Product # 62-0691-82) and 0.5 µg of Rat IgG2a kappa Isotype Control, PE (Product # 12-4321-82) (left) or 0.5 µg of CD186 (CXCR6) Monoclonal Antibody, PE (right). Cells in the CD3+ gate were used for analysis.
产品信息
12-9186-82
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
DANID2
抗原
Mammalian cell line expressing the full form of CD186
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Description: This DANID2 monoclonal antibody recognizes mouse CD186, also known as CXCR6. This DANID2 antibody will work in flow cytometry on both native and paraformaldehyde-fixed cells.
Applications Reported: This DANID2 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This DANID2 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 1.0 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
靶标信息
CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV. CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells. It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186. The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells and liver endothelial cells. Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 6; CC motif chemokine; CCmotif chemokine; CD186; CD186 antigen; CXC; CXC motif chemokine; CXC-R6; CXCR-6; OTTHUMP00000209997; OTTHUMP00000209998
基因别名: BB217514; BONZO; Cxcr6; STRL33
UniProt ID: (Mouse) Q9EQ16
Entrez Gene ID: (Mouse) 80901
