A Mammalian H+ Channel Generated Through Alternative Splicing of the NADPH Oxidase HomologNOH-1
AuthorsBanfi B, Maturana A, Jaconi S, Arnaudeau S, Laforge T, Sinha B, Ligeti E, Demaurex N, Krause KH
JournalScience
PubMed ID10615049
'Voltage-gated proton (H+) channels are found in many human and animal tissues and play an important role in cellular defense against acidic stress. However, a molecular identification of these unique ion conductances has so far not been achieved. A 191-amino acid protein is described that, upon heterologous expression, has properties ... More