Identifying genes of agronomic importance in maize by screening microsatellites for evidence of selection during domestication.
Authors Vigouroux Y; McMullen M; Hittinger C T; Houchins K; Schulz L; Kresovich S; Matsuoka Y; Doebley J;
JournalProc Natl Acad Sci U S A
PubMed ID12105270
'Crop species experienced strong selective pressure directed at genes controlling traits of agronomic importance during their domestication and subsequent episodes of selective breeding. Consequently, these genes are expected to exhibit the signature of selection. We screened 501 maize genes for the signature of selection using microsatellites or simple sequence repeats ... More
Pattern of diversity in the genomic region near the maize domestication gene tb1.
AuthorsClark RM, Linton E, Messing J, Doebley JF,
JournalProc Natl Acad Sci U S A
PubMed ID14701910
Domesticated maize and its wild ancestor (teosinte) differ strikingly in morphology and afford an opportunity to examine the connection between strong selection and diversity in a major crop species. The tb1 gene largely controls the increase in apical dominance in maize relative to teosinte, and a region of the tb1 ... More
Transforming growth factor-ß is required for vasculogenic mimicry formation in glioma cell line U251MG.
AuthorsLing G, Wang S, Song Z, Sun X, Liu Y, Jiang X, Cai Y, Du M, Ke Y,
JournalCancer Biol Ther
PubMed ID22104964
Both vasculogenic mimicry (VM) and transforming growth factor-ß (TGFß) are positively correlated with malignancy in glioma. Accordingly, we supposed that TGFß might be related with VM, and aimed to detect whether TGFß could influence VM formation in two glioma cell lines U251MG and SHG44, which were different in malignancy. We ... More