CD40-mediated Activation of NF-kappa B in Airway Epithelial Cells.
Authors Propst Stacie M; Estell Kim; Schwiebert Lisa M;
JournalJ Biol Chem
PubMed ID12122011
We have reported previously that airway epithelial cells (AEC) express CD40 and that activation of this molecule stimulates the expression of inflammatory mediators, including the chemokine RANTES (regulated on activation normal T cell expressed and secreted). Because NF-kappaB regulates the expression of many inflammatory mediators, such as RANTES, we utilized ... More