The Low Density Lipoprotein Receptor-related Protein Mediates Fibronectin Catabolism and Inhibits Fibronectin Accumulation on Cell Surfaces.
Authors Salicioni Ana M; Mizelle Kellie S; Loukinova Elena; Mikhailenko Irina; Strickland Dudley K; Gonias Steven L;
JournalJ Biol Chem
PubMed ID11867643
Low density lipoprotein receptor-related protein (LRP) is a member of the low density lipoprotein receptor family, which functions as an endocytic receptor for diverse ligands. In this study, we demonstrate that murine embryonic fibroblasts (MEF-2 cells) and 13-5-1 Chinese hamster ovary cells, which are LRP-deficient, accumulate greatly increased levels of ... More