Select a microplate that is compatible with your instrument. Refer to the manufacturer's manual for types of microplates that are recommended for use with your instrument.
Various types of plastic may autofluoresce. Select a microplate that is rated for fluorescence-based assays and exhibits little or no autofluorescence in the emission range of the reagent you wish to use.
Clear plates are routinely used for fluorescence-based assays, but opaque-walled microplates reduce bleed-through between wells. If you are using live cells, you may need to consider special substrate treatments for the bottom of the wells, such as poly-L-lysine.
Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.