Vascular endothelial growth factor-A is expressed both on lymphoma cells and endothelial cells in angioimmunoblastic T-cell lymphoma and related to lymphoma progression.
AuthorsZhao WL, Mourah S, Mounier N, Leboeuf C, Daneshpouy ME, Legrès L, Meignin V, Oksenhendler E, Maignin CL, Calvo F, Brière J, Gisselbrecht C, Janin A,
JournalLab Invest
PubMed ID15311211
Vascular endothelial growth factor-A (VEGF-A), a main stimulator of endothelial cell proliferation, plays an important role on tumor angiogenesis. Angioimmunoblastic T-cell lymphoma (AITL) show the most prominent vascular component among lymphomas and their prognosis is difficult to predict. To assess the clinical significance of VEGF-A in AITL, VEGF-A gene expression ... More