High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss.
AuthorsMaitra A, Wistuba II, Washington C, Virmani AK, Ashfaq R, Milchgrub S, Gazdar AF, Minna JD,
JournalAm J Pathol
PubMed ID11438460
'We performed high-resolution allelotyping for loss of heterozygosity (LOH) analysis on microdissected samples from 45 primary breast cancers, 47 mammary preneoplastic epithelial foci, and 18 breast cancer cell lines, using a panel of 27 polymorphic chromosome 3p markers. Allele loss in some regions of chromosome 3p was detected in 39 ... More
Influence of estrus of dairy goats on somatic cell count, milk traits, and sex steroid receptors in the mammary gland.
AuthorsMoroni P, Pisoni G, Savoini G, van Lier E, Acuña S, Damián JP, Meikle A,
JournalJ Dairy Sci
PubMed ID17235156
Two experiments were conducted to study the effect of the stage of a spontaneous estrus cycle on milk yield and constituents [somatic cell count (SCC), fat, protein, caseins, lactose, and urea content] and on estrogen receptor-alpha (ERalpha ) and progesterone receptor (PR) immunostaining in the mammary gland. In experiment I, ... More
Elevated mammaglobin (h-MAM) expression in breast cancer is associated with clinical and biological features defining a less aggressive tumour phenotype.
AuthorsNúñez-Villar MJ, Martínez-Arribas F, Pollán M, Lucas AR, Sánchez J, Tejerina A, Schneider J,
JournalBreast Cancer Res
PubMed ID12793902
Mammaglobin (h-MAM) is expressed mainly by breast epithelial cells, and this feature has been used to detect circulating breast cancer cells and occult metastases in sentinel axillary lymph nodes of breast cancer patients. However, the biological role of mammaglobin is completely unknown. We studied 128 fresh-frozen breast cancer specimens by ... More