c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases.
AuthorsTakeuchi H, Bilchik A, Saha S, Turner R, Wiese D, Tanaka M, Kuo C, Wang HJ, Hoon DS,
JournalClin Cancer Res
PubMed ID12684423
'Both c-MET and vascular endothelial growth factor (VEGF)-C expression are important factors in primary carcinoma progression. We hypothesized that overexpression of c-MET and/or VEGF-C mRNA in primary colorectal cancer (CRC) can predict tumor invasion and regional metastasis. The level of c-MET and VEGF-C mRNA expression was assessed using a quantitative ... More