Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas and squamous cell carcinomas of the lung.
AuthorsGomes A, Reis-Silva M, Alarcão A, Couceiro P, Sousa V, Carvalho L,
Journal
PubMed ID24360395
'Five years survival of lung cancer is 16%, significantly lower than in prostate (99.9%), breast (88.5%) and colon (64.1%) carcinomas. When diagnosed in the surgical stage it increases to 50% but this group only comprises 14-16% of the cases. DNA methylation has emerged as a potential cancer-specific biomarker. Hypermethylation of ... More
Filiform polyposis: A benign entity? Case report and literature review.
AuthorsBoulagnon C, Jazeron JF, Diaz-Cives A, Ehrhard F, Bouché O, Diebold MD
Journal
PubMed ID24315830
Filiform polyposis (FP) is a distinctive and unusual form of benign non syndromic polyposis that is occasionally encountered in the colon of patients with inflammatory bowel disease (IBD) history. FP is characterized by one to hundreds, slender, arborizing, vermiform projections in the colon lined by normal or inflammatory colonic mucosa. ... More