Novel expression of claudin-5 in glomerular podocytes.
AuthorsKoda R, Zhao L, Yaoita E, Yoshida Y, Tsukita S, Tamura A, Nameta M, Zhang Y, Fujinaka H, Magdeldin S, Xu B, Narita I, Yamamoto T
JournalCell Tissue Res
PubMed ID21271259
'Tight junctions are the main intercellular junctions of podocytes of the renal glomerulus under nephrotic conditions. Their requisite components, claudins, still remain to be identified. We have measured the mRNA levels of claudin subtypes by quantitative real-time PCR using isolated rat glomeruli. Claudin-5 was found to be expressed most abundantly ... More
Tight junction proteins vary in the choroid plexus of ewes according to photoperiod.
AuthorsLagaraine C, Skipor J, Szczepkowska A, Dufourny L, Thiery JC
JournalBrain Res
PubMed ID21529785
'Sheep from temperate latitudes exhibit seasonal variations in many physiological functions such as reproduction, food intake, body weight, and pelage growth. Majority of seasonal changes are controlled by the annual photoperiodic cycle and melatonin secretion. For reproduction, the resulting key event is a modulation of the negative feedback of steroids ... More
Expression of claudins 1, 2, 3, 4, 5 and 7 in various types of tumours.
AuthorsSoini Y
JournalHistopathology
PubMed ID15842637
Claudins are adhesion molecules present in tight junctions. To evaluate their usefulness as differentiation markers claudins 1, 2, 3, 4, 5 and 7 were studied in 116 epithelial and 92 non-epithelial tumours. ... More
Transmigration of neural stem cells across the blood brain barrier induced by glioma cells.
AuthorsDíaz-Coránguez M, Segovia J, López-Ornelas A, Puerta-Guardo H, Ludert J, Chávez B, Meraz-Cruz N, González-Mariscal L,
JournalPLoS One
PubMed ID23637756
Transit of human neural stem cells, ReNcell CX, through the blood brain barrier (BBB) was evaluated in an in vitro model of BBB and in nude mice. The BBB model was based on rat brain microvascular endothelial cells (RBMECs) cultured on Millicell inserts bathed from the basolateral side with conditioned ... More
Two strikingly different signaling pathways are induced by meningococcal type IV pili on endothelial and epithelial cells.
AuthorsLécuyer H, Nassif X, Coureuil M
JournalInfect Immun
PubMed ID22064711
Following adhesion on brain microvasculature, Neisseria meningitidis is able to cross the blood-brain barrier (BBB) by recruiting the polarity complex and the cell junction proteins, thus allowing the opening of the paracellular route. This feature is the consequence of the activation by the type IV pili of the ß2-adrenergic receptor/ß-arrestin ... More