Expression of activin A and follistatin core proteins by human prostate tumor cell lines.
AuthorsMcPherson SJ, Mellor SL, Wang H, Evans LW, Groome NP, Risbridger GP
JournalEndocrinology
PubMed ID10537161
'Activin and follistatin (FS) messenger RNA and protein are expressed and localized to human prostate tissue from men with high grade cancer and to human prostate tumor cell lines LNCaP, DU145, and PC3. Although activin A induces apoptosis and inhibits cell proliferation in LNCaP cells, PC3 cells are insensitive to ... More
Pathology and localization of simian immunodeficiency virus in the reproductive tract of chronically infected male rhesus macaques.
AuthorsMiller CJ, Vogel P, Alexander NJ, Dandekar S, Hendrickx AG, Marx PA
JournalLab Invest
PubMed ID8139266
Despite the fact that human immunodeficiency virus (HIV) is transmitted by sexual contact, the biology of this mode of transmission remains largely undefined. HIV is present in semen in both cell-free and cell-associated forms and can be isolated from asymptomatic individuals and AIDS patients. The source of HIV in semen ... More