Long-term antibody and immune memory response induced by pulmonary delivery of the influenza Iscomatrix vaccine.
AuthorsVujanic A, Snibson KJ, Wee JL, Edwards SJ, Pearse MJ, Scheerlinck JP, Sutton P
JournalClin Vaccine Immunol
PubMed ID22072721
'Pulmonary delivery of an influenza Iscomatrix adjuvant vaccine induces a strong systemic and mucosal antibody response. Since an influenza vaccine needs to induce immunological memory that lasts at least 1 year for utility in humans, we examined the longevity of the immune response induced by such a pulmonary vaccination, with ... More
The carboxyl-terminal sequence of the human secretory mucin, MUC6. Analysis Of the primary amino acid sequence.
AuthorsToribara NW, Ho SB, Gum E, Gum JR, Lau P, Kim YS
JournalJ Biol Chem
PubMed ID9195947
The distribution of MUC6 suggests that its primary function is protection of vulnerable epithelial surfaces from damaging effects of constant exposure to a wide range of endogenous caustic or proteolytic agents. A combination of genomic, cDNA. and 3' rapid amplification of cDNA ends techniques was used to isolate the carboxyl-terminal ... More