Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy.
Authors Suzuki Miwako; Carlson Kerri M; Marchuk Douglas A; Rockman Howard A;
JournalCirculation
PubMed ID11956126
'BACKGROUND: Understanding the role for genetic factors in human heart failure is difficult because environmental factors cannot be standardized and genetic variation is great. One approach to identify genes that modify disease outcome is to use mouse models that show strong genetic variation of the disease phenotype. METHODS AND RESULTS: ... More