Hepatitis C virus subgenomic replicons in the human embryonic kidney 293 cell line.
AuthorsAli S, Pellerin C, Lamarre D, Kukolj G,
JournalJ Virol
PubMed ID14671129
'Hepatitis C virus (HCV) infects liver cells and its replication in other cells is incompletely defined. Human hepatoma Huh-7 cells harboring subgenomic HCV replicons were used in somatic cell fusion experiments with human embryonic kidney 293 cells as a means of examining the permissiveness of 293 cells for HCV subgenomic ... More
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.
AuthorsAktas T, Avsar Ilik I, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, Manke T, Backofen R, Akhtar A
JournalNature
PubMed ID28355180
Transposable elements are viewed as 'selfish genetic elements', yet they contribute to gene regulation and genome evolution in diverse ways. More than half of the human genome consists of transposable elements. Alu elements belong to the short interspersed nuclear element (SINE) family of repetitive elements, and with over 1?million insertions ... More
Structures of the Human PGD
AuthorsWang L, Yao D, Deepak RNVK, Liu H, Xiao Q, Fan H, Gong W, Wei Z, Zhang C