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引用和文献 (5)
Thermo Scientific™
SIAB（琥珀酰亚胺基(4-碘乙酰基)氨基苯甲酸酯）
Thermo Scientific Pierce SIAB is a mid-length (10.6 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive了解更多信息
| 货号 | 数量 |
|---|---|
| 22329 | 50 mg |
货号 22329
价格（CNY)
4,335.00
飞享价
Ends: 31-Dec-2026
5,858.00共减 1,523.00 (26%)
Each
数量:
50 mg
价格（CNY)
4,335.00
飞享价
Ends: 31-Dec-2026
5,858.00共减 1,523.00 (26%)
Each
Thermo Scientific Pierce SIAB is a mid-length (10.6 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
Features of SIAB:
• Reactive groups: NHS ester and iodoacetyl
• Reactive toward: amino and sulfhydryl groups
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-SIAB
• Used to prepare stable enzyme-IgG conjugates
• Forms conjugates with liposomes
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-SIAB (sulfosuccinimidyl (4-iodoacetyl)aminobenzoate)
Features of SIAB:
• Reactive groups: NHS ester and iodoacetyl
• Reactive toward: amino and sulfhydryl groups
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-SIAB
• Used to prepare stable enzyme-IgG conjugates
• Forms conjugates with liposomes
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
Sulfo-SIAB (sulfosuccinimidyl (4-iodoacetyl)aminobenzoate)
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性是
描述SIAB
形式粉末
标记方法化学标记
分子量402.14
聚乙二醇化否
产品线Pierce
数量50 mg
反应一部分卤乙酰,NHS 酯
运输条件环境
溶解度DMF、DMSO
间隔臂长10.6 Å
水溶性否
化学反应性胺-巯基
可裂解否
交联剂类型异型双功能团试剂
产品规格标准
产品类型交联剂
间隔子中等（10 至 30 Å）
Unit SizeEach
内容与储存
接收后，在 4°C 下避光储存。
引用和文献 (5)
引用和文献
Abstract
Chip-based genotyping by mass spectrometry.
Journal:Proc Natl Acad Sci U S A
PubMed ID:10468554
Silicon chips with immobilized target DNAs were used for accurate genotyping by mass spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were covalently attached to chip wells via N-succinimidyl (4-iodoacetyl)aminobenzoate (SIAB) chemistry. Primer annealing, extension, and termination were performed on a 1-microl scale directly in the chip
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film
Gbeta subunit interacts with a peptide encoding region 956-982 of adenylyl cyclase 2. Cross-linking of the peptide to free Gbetagamma but not the heterotrimer.
Journal:J Biol Chem
PubMed ID:8900107
The region encoded by amino acids 956-982 of adenylyl cyclase 2 is important for Gbetagamma stimulation. Interactions of a peptide encoding the 956-982 region of adenylyl cyclase 2 (QEHAQEPERQYMHIGTMVEFAYALVGK (QEHA peptide)) with Gbetagamma subunits were studied. QEHA peptide was covalently attached to beta subunit of free Gbetagamma by the cross-linker
Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex.
Journal:Mol Cell Biol
PubMed ID:12640110
BCS1, a component of the inner membrane of mitochondria, belongs to the group of proteins with internal, noncleavable import signals. Import and intramitochondrial sorting of BCS1 are encoded in the N-terminal 126 amino acid residues. Three sequence elements were identified in this region, namely, the transmembrane domain (amino acid residues
Use of immobilized PCR primers to generate covalently immobilized DNAs for in vitro transcription/translation reactions.
Journal:Nucleic Acids Res
PubMed ID:10606673
We have developed a novel biochemical method to simultaneously amplify and immobilize a target gene onto insoluble particles using PCR. This method employs the covalent attachment of one of two PCR primers to a particle surface either directly during DNA synthesis of the primer or post-DNA synthesis, through the use