BMH（双马来酰亚胺基己烷）
BMH（双马来酰亚胺基己烷）
引用和文献 (4)
Thermo Scientific™

BMH（双马来酰亚胺基己烷）

Thermo Scientific Pierce BMH 是一种长臂的马来酰亚胺交联剂，用于巯基（例如蛋白或肽半胱氨酸）之间共价、不可逆的偶联。BMH 的特点：•反应性基团：马来酰亚胺了解更多信息
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货号数量
2233050 mg
货号 22330
价格（CNY)
2,586.00
Each
添加至购物车
数量:
50 mg
请求批量或定制报价
价格（CNY)
2,586.00
Each
添加至购物车
Thermo Scientific Pierce BMH 是一种长臂的马来酰亚胺交联剂，用于巯基（例如蛋白或肽半胱氨酸）之间共价、不可逆的偶联。

BMH 的特点：

•反应性基团：马来酰亚胺（两端）
•可与以下基团发生反应：巯基
•长 (13.0Å) 的巯基-巯基交联剂，由马来酰亚胺基团和 11 原子间隔臂组成
• 不溶于水—首先溶于 DMF 或 DMSO 中，然后添加至水性反应缓冲液
• 不可切割

交联剂应用指南 -- 检索本产品的最新参考文献

相关产品
BMB（1,4-双马来酰亚胺基丁烷）
BMOE（双马来酰亚胺基乙烷）
BM(PEG)2（1,8-双马来酰亚胺基-二乙二醇）
BM(PEG)3（1,11-双马来酰亚胺基-三乙二醇）
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性是
描述BMH
形式粉末
标记方法化学标记
分子量276.29
聚乙二醇化否
产品线Pierce
数量50 mg
反应一部分马来酰亚胺
运输条件环境
溶解度DMF、DMSO
间隔臂长13.0 Å
水溶性否
化学反应性巯基-巯基
可裂解否
交联剂类型同型双功能团试剂
产品规格标准
产品类型交联剂
间隔子中等（10 至 30 Å）
Unit SizeEach
内容与储存
接收后，储存在 4°C 下。

常见问题解答 (FAQ)

Can you provide the shelf-life for BMH (bismaleimidohexane)?

BMH (bismaleimidohexane) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用和文献 (4)

引用和文献
Abstract
Membrane curvature induced by Arf1-GTP is essential for vesicle formation.
Authors:Beck R, Sun Z, Adolf F, Rutz C, Bassler J, Wild K, Sinning I, Hurt E, Brügger B, Béthune J, Wieland F
Journal:Proc Natl Acad Sci U S A
PubMed ID:18689681
'The GTPase Arf1 is considered as a molecular switch that regulates binding and release of coat proteins that polymerize on membranes to form transport vesicles. Here, we show that Arf1-GTP induces positive membrane curvature and find that the small GTPase can dimerize dependent on GTP. Investigating a possible link between ... More
The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.
Authors:Ahmad R, Alam M, Rajabi H, Kufe D
Journal:J Biol Chem
PubMed ID:22544745
'The pro-apoptotic BAX protein contains a BH3 domain that is necessary for its dimerization and for activation of the intrinsic apoptotic pathway. The MUC1 (mucin 1) heterodimeric protein is overexpressed in diverse human carcinomas and blocks apoptosis in the response to stress. In this study, we demonstrate that the oncogenic ... More
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis.
Authors:Kida Y, Morimoto F, Sakaguchi M
Journal:J Cell Biol
PubMed ID:18166653
During protein integration into the endoplasmic reticulum, the N-terminal domain preceding the type I signal-anchor sequence is translocated through a translocon. By fusing a streptavidin-binding peptide tag to the N terminus, we created integration intermediates of multispanning membrane proteins. In a cell-free system, N-terminal domain (N-domain) translocation was arrested by ... More
Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation.
Authors:Gogada R, Prabhu V, Amadori M, Scott R, Hashmi S, Chandra D
Journal:J Biol Chem
PubMed ID:21712378
Resveratrol, a naturally occurring phytoalexin, is known to induce apoptosis in multiple cancer cell types, but the underlying molecular mechanisms remain unclear. Here, we show that resveratrol induced p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated translocation of Bax to mitochondria where it underwent oligomerization to initiate apoptosis. Resveratrol treatment promoted ... More