The S18 ribosomal protein is a putative substrate for Ca2+/calmodulin-activated protein kinase II.
Authors Mishra-Gorur Ketu; Singer Harold A; Castellot John J Jr;
JournalJ Biol Chem
PubMed ID12145273
'The delta-isoform of Ca(2+)/calmodulin-activated protein kinase II (CaMK II) is abundantly expressed in vascular smooth muscle, but relatively little is known about its regulation or its potential cellular substrates. There are few, if any, known substrates of CaMK II that are physiologically relevant in vascular smooth muscle cells. Studies presented ... More
The expression of Sprouty1, an inhibitor of fibroblast growth factor signal transduction, is decreased in human prostate cancer.
AuthorsKwabi-Addo B, Wang J, Erdem H, Vaid A, Castro P, Ayala G, Ittmann M,
JournalCancer Res
PubMed ID15256439
A considerable body of evidence indicates that alterations of fibroblast growth factors (FGFs) and their receptors contribute to prostate cancer progression. Recently, a new family of regulators of FGF activity has been identified. The Sprouty gene family negatively regulates FGF signaling in a variety of systems and could potentially limit ... More