TheraPure™ rU 亚磷酰胺,20-400 螺纹瓶
Thermo Scientific™

TheraPure™ rU 亚磷酰胺,20-400 螺纹瓶

rU CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) for use in oligonucleotide synthesis.
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货号数量
27-1804-101 g
货号 27-1804-10
价格(CNY)
204.00
Each
数量:
1 g
价格(CNY)
204.00
Each

rU CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) for use in oligonucleotide synthesis. RNA phosphoramidites contain a 2'-OH protecting group, tBDMS (tert-butyl dimethylsilyl). Each base has unique protecting groups (except T and U) designed specifically to protect the RNA during the chemical synthesis process, and produce the highest amount of full length product. Alternate base protection options are also available to allow for faster deprotection and longer oligonucleotide synthesis. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30 mL Amber bottle with a 20-400 Finish neck style, which is compatible with most Expedite Systems of oligonucleotide synthesizers.

Features:

  • HPLC Purity: ≥99%
  • M-11 Impurity: ≤0.01%
  • 31P NMR Purity: ≥99%
  • Sum of non-primary peaks in 140-152 ppm range: ≤0.5%
  • No single PIII impurity >0.3%
rU CEP 是一种亚磷酰胺,含 5' DMT 和尿苷 (U),用于合成寡核苷酸。RNA 亚磷酰胺含有 2'-OH 保护基团、tBDMS(叔丁基二甲基硅烷基)。每种碱基都具有独特的保护基团(T 和 U 除外),专用于在化学合成过程中保护 RNA,以及产生较高量的全长产物。也提供其他碱基保护,以实现脱保护,延长寡核苷酸合成。带有 TheraPure 商标的产品亚磷酰胺纯度均较高,因为在开发这种产品时,采用的是严格度较高的高分辨率分析方法,并且对杂质谱也进行了严格控制,因此,适用于任何治疗性应用。该产品以 30 mL 琥珀色瓶装,采用 20-400 螺纹瓶颈样式,与大多数寡核苷酸合成仪的 Expedite 系统兼容。

特点:
•化学全称—5'-O-(4,4'-二甲氧基三苯甲基)-2'-O-[(叔丁基)二甲基硅烷基]-尿苷-3'-O-[(2-氰乙基)-(N,N-二异丙基)]-亚磷酰胺
• 分子式—C45H61N4O9PSi
• 碱基—rU
• 化学式量—861.1 g/mol
• CAS 号—118362-03-1
• HPLC 纯度—≥99%;M-11 杂质:≤0.01%
• 31P NMR 纯度—≥99%;140-152 ppm 的非主峰总和:≤0.5%;无单个 PIII 杂质 >0.3%

仅供科研使用。不可用于诊断程序。
规格
31P NMR 纯度≥99%
CAS118362-03-1
化学名称或材料5'-O-(4,4'-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-uridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
描述Base: rU
适用于(应用)Oligonucleotide synthesis
适用于(设备)Expedite 合成仪
形式Powder
产品规格粉末
分级TheraPure™
分子式C45H61N4O9Psi
分子量861.1 g/mol
核酸类型RNA
核苷类型尿苷 (U)
产品类型rU CEP
纯度99%
数量1 g
试剂类型亚磷酰胺
运输条件室温
产品线TheraPure
Unit SizeEach
内容与储存
在冰箱(-20°C 或以下)中储存。