cGMP 生产和质量体系 IMDM 在位于纽约格兰德岛上符合 cGMP 要求的工厂内生产。该工厂是在 FDA 注册的医疗器械生产商,通过 ISO 13485 标准认证。为确保供应链连续性,我们同时提供由我们的苏格兰工厂生产的等同 IMDM 产品 (31980-048)。该工厂也是在 FDA 注册的医疗器械生产商,且通过 ISO 13485 标准认证。
Characterization of the laminin binding domains of the Lutheran blood group glycoprotein.
Authors:El Nemer W, Gane P, Colin Y, D'Ambrosio AM, Callebaut I, Cartron JP, Van Kim CL,
Journal:J Biol Chem
PubMed ID:11319237
'Lutheran (Lu) blood group antigens and the basal cell adhesion molecule antigen reside on two glycoproteins that belong to the Ig superfamily (IgSF) and carry five Ig-like extracellular domains. These glycoproteins act as widely expressed adhesion molecules and represent the unique receptors for laminin-10/11 in erythroid cells. Here, we report ... More
Specificity and affinity motifs for Grb2 SH2-ligand interactions.
Authors: Kessels Helmut W H G; Ward Alister C; Schumacher Ton N M;
Journal:Proc Natl Acad Sci U S A
PubMed ID:12084912
Protein-protein interactions are often mediated by the recognition of short continuous amino acid stretches on target proteins by specific binding domains. Affinity-based selection strategies have successfully been used to define recognition motifs for a large series of such protein domains. However, in many biological systems specificity of interaction may be ... More
Antigenic and Functional Properties of the Human Red Blood Cell Urea Transporter hUT-B1.
The Kidd (JK) blood group locus encodes the urea transporter hUT-B1, which is expressed on human red blood cells and other tissues. The common JK*A/JK*B blood group polymorphism is caused by a single nucleotide transition G838A changing Asp-280 to Asn-280 on the polypeptide, and transfection of erythroleukemic K562 cells with ... More