A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells.
AuthorsStraub BK, Boda J, Kuhn C, Schnoelzer M, Korf U, Kempf T, Spring H, Hatzfeld M, Franke WW,
JournalJ Cell Sci
PubMed ID14625392
The anucleate prismoid fiber cells of the eye lens are densely packed to form a tissue in which the plasma membranes and their associated cytoplasmic coat form a single giant cell-cell adhesive complex, the cortex adhaerens. Using biochemical and immunoprecipitation methods in various species (cow, pig, rat), in combination with ... More
Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-ß production and epithelial to mesenchymal transition.
AuthorsSchneider DJ, Wu M, Le TT, Cho SH, Brenner MB, Blackburn MR, Agarwal SK,
JournalFASEB J
PubMed ID21990376
Pulmonary fibrosis, characterized by excess deposition of extracellular matrix by myofibroblasts, is a serious component of chronic lung diseases. Cadherin-11 (CDH11) is increased in wound healing and fibrotic skin. We hypothesized that CDH11 is increased in pulmonary fibrosis and contributes its development. CDH11 expression was assessed in lung tissue from ... More
Cadherin expression in the developing mouse olfactory system.
AuthorsAkins MR, Benson DL, Greer CA
JournalJ Comp Neurol
PubMed ID17278136
Although odor receptors have been implicated in establishing the topography of olfactory sensory neurons (OSNs) in the olfactory bulb (OB), it is likely other molecules are also involved. The cadherins (CDHs) are a large family of cell adhesion molecules that mediate cell:cell interactions elsewhere in the central nervous system. However, ... More