Image-based assessment of growth and signaling changes in cancer cells mediated by direct cell-cell contact.
AuthorsLapan P, Zhang J, Hill A, Zhang Y, Martinez R, Haney S,
JournalPLoS One
PubMed ID19774227
'Many important biological processes are controlled through cell-cell interactions, including the colonization of metastatic tumor cells and the control of differentiation of stem cells within their niche. Despite the crucial importance of the cellular environment in regulating cellular signaling, in vitro methods for the study of such interactions are difficult ... More